ProCas9 Sensor (IMAGE)

University of California - Berkeley

ProCas9 Sensor

Caption

ProCas9 can sense the presence of an enzyme called a protease. ProCas9 (left, gray) is inactive until the protease snips a short piece of protein (red loop), at which point it becomes active (right, red) and binds DNA. By making the Cas9 fluoresce when it binds DNA, researchers get a signal that the protease is present.

Credit

UC Berkeley

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