Unique Pattern of Brain Inflammation (IMAGE) Elsevier Caption Combination antiretroviral therapy (cART)-treated animals show a distinct pattern of inflammation compared to classic simian immunodeficiency virus encephalitis. In cART-treated animals, no giant cells and few macrophages are seen. Instead, inflammation consists of lymphocyte-rich cuffs expanding perivascular spaces. Credit Joseph L. Mankowski Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.