Every Atom Counts (IMAGE)

European Molecular Biology Laboratory

Every Atom Counts

Caption

Tailored parallel X-rays perfectly matching the dimensions of the protein crystals enabled the scientists to determine the proteasome structure in unprecedented detail (top right). They could show that a 7-ring is formed by the reaction of the inhibitor with the proteasome (bottom). This knowledge paves the way for the design of new therapeutics.

Credit

Hartmut Sebesse / Max Planck Institute for Biophysical Chemistry

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