Figure 1: Formation Model of the Autophagy Initiation Machinery (IMAGE)

_Tokyo Institute of Technology

Figure 1: Formation Model of the Autophagy Initiation Machinery

Caption

Under nutrient-rich conditions, Atg1, Atg13 and the Atg17-29-31 subcomplex exist without interacting with each other. Upon autophagy induction, under conditions such as starvation, they form a pentameric complex, which further assembles into a giant autophagy initiation machinery complex.

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Developmental Cell

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