Cis P-tau accumulates in dementia-damaged neurons. (IMAGE)

Medical University of South Carolina

Cis P-tau accumulates in dementia-damaged neurons.

Caption

The cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzheimer's disease (AD) and mixed AD and VCID brains, but was detected in the absence of other tau isoforms in VCID brains.

Credit

Image provided by Dr. Onder Albayram of the Medical University of South Carolina.

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