Rat Nucleus Accumbens (IMAGE) Society for Neuroscience Caption CRISPR activation enables flexible upregulation of selected genes in cultured neurons and the adult nervous system. Here, neurons in the rat nucleus accumbens (a key brain reward structure) were targeted for CRISPR-based gene activation. Fluorescent reporter molecules mark the protein product of a gene targeted for activation (green), neurons expressing a CRISPR guide RNA (red), and DNA (blue). Credit Katherine Savell & Nancy Carullo, Day Lab, University of Alabama at Birmingham Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.