Image of Brain (IMAGE)

NIH/National Institute of Diabetes and Digestive and Kidney Diseases

Image of Brain

Caption

Dopamine signaling is thought to play a central role in orchestrating the processes of reward, motivation and habit formation. The depicted orange/yellow regions indicate where brain dopamine activity was positively related to obesity. These areas include the dorsolateral striatum which mediates the process of habit formation. The blue regions show where dopamine activity was negatively related to obesity and includes the ventromedial striatum, a brain region that controls reward and motivation.

Credit

Juen Guo, Ph.D. and W. Kyle Simmons, Ph.D.

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