Breast Cells Stained for Keratin in Older and Younger Women (IMAGE)
Caption
Histological sections of normal breast show lobules from a 37-year-old woman (top) and a 76-year-old woman that were stained to show how the expression of a keratin protein (brown) changes with age. In young women, this protein is only in the outer layer of cells surrounding the inner layer of milk-producing cells. In older women even the milk-producing cells make the protein. This age-related cellular change is a factor that may increase the potential for malignant transformation in older women.
Credit
Image from Mark LaBarge, Berkeley Lab, and Alexander Barowsky, UC Davis
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