Blocking microRNA Allows ES Cells to Develop Extra-embryonic Tissues (IMAGE)

University of California - Berkeley

Blocking microRNA Allows ES Cells to Develop Extra-embryonic Tissues

Caption

miR-34a-deficient embryonic stem cell culture is enriched with cells with expanded developmental potential as shown by their strong MuERV-L induction (red). These cells are distinct from the classic embryonic stem cells shown by the Oct4 staining (green). MuERV-L are the family of murine endogenous retroviruses activated in the very early embryo.

Credit

Lin He, UC Berkeley

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