The Mechanism by Which Group A <i>Streptococcus</i> (GAS) Evades the Immune System. (IMAGE)

The University of Osaka

The Mechanism by Which Group A <i>Streptococcus</i> (GAS) Evades the Immune System.

Caption

The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and then activates the immune system to eliminate the invading pathogen. However, DGDG, an antagonistic lipid present on GAS, inhibits Mincle activity, thereby evading the host immune system.

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Osaka University

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