Chemistry of a Disease (IMAGE)
Caption
University of Iowa chemists have unraveled the chemistry underlying how some deadly diseases, such as tuberculosis, produce thymine, a DNA base critical for these diseases to survive and reproduce. The team found these diseases use a different chemical pathway that involves an enzymatic relay system called flavin. The finding could help drug companies target the chemical reaction, rather than testing millions of compounds, to stop these diseases.
Credit
Amnon Kohen lab, University of Iowa
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