Kateagis Graphic (IMAGE) University of California - San Diego Caption In kataegis, multiple mutations cluster in a few hotspots in a cancer genome. Here, cytosine (C) bases are commonly substituted with thymine (T) in the DNA strand. Credit Matteo D'Antonio Usage Restrictions Use caption and photo credit as indicated. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.