Silencing TAZ Reverses Liver Fibrosis (IMAGE)

Columbia University Irving Medical Center

Silencing TAZ Reverses Liver Fibrosis

Caption

Mice were fed a diet rich in fat and sugar until they developed NASH-like features in their livers. On the left, staining reveals the most important feature of NASH -- fibrosis -- as dark linear structures (indicated with arrows). On the right, fibrosis reverted when TAZ was silenced in the mice with NASH.

Credit

Source: Dr. Wang in the Tabas lab, Columbia University Medical Center

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