Fractal dimensions of tics (IMAGE)

Washington University in St. Louis

Fractal dimensions of tics

Caption

(a) Change in fractal dimension between screening and 12-month visit (ΔDf) as a function of change in YGTSS TTS (ΔTTS (b) Comparison of average Df for the patients under various suppression conditions during screening visits shows that DRO led to the most effective tic suppression (largest Df). Additionally, the fractal dimension of all suppression conditions increased at 12 months (when most patients met diagnostic criteria for TS). Error bars show 95% confidence intervals. (c,d) Rater-blind reproducibility of Df as an assessment tool. Comparison of Df for tic time series generated by two examiners, with examiner 2 being blind to visit and condition. Good agreement is observed between examiners, verifying inter-rater reliability of results. Error bars show 95% confidence intervals.

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Rajan Chakrabarty, Kevin Black

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