Derivation of Induced Pluripotent Stem Cells With NBS and Their Differentiation into Early Neurons (IMAGE)

Heinrich-Heine University Duesseldorf

Derivation of Induced Pluripotent Stem Cells With NBS and Their Differentiation into Early Neurons

Caption

A. Skin cells from NBS patients were reprogrammed into induced pluripotent stem cells that form a round, flat colony and stained positive for alkaline phosphatase activity, an early marker for pluripotency. B. The induced pluripotent stem cells with NBS were then differentiated into early neurons, showing the formation of neural rosettes and neurons. These cells were stained positive for NCAM1 (red), a protein expressed in early neurons (nuclei stained in blue).

Credit

Tomer Halevy et. al.

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