Restored Functional Cornea (IMAGE)

Mass Eye and Ear

Restored Functional Cornea

Caption

This is a restored functional cornea following transplantation of human ABCB5-positive limbal stem cells to limbal stem cell-deficient mice. Transplants consisting of human ABCB5-positive limbal stem cells resulted in restoration and long-term maintenance of a normal clear cornea, whereas control mice that received either no cells or ABCB5-negative cells failed to restore the cornea.

Credit

Kira Lathrop, Bruce Ksander, Markus Frank, and Natasha Frank.

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