Visualizing Transcription in An Embryonic Cell (IMAGE)

California Institute of Technology

Visualizing Transcription in An Embryonic Cell

Caption

Intron seqFISH enables 3D reconstruction of nascent transcription active sites (colored spots) in an embryonic stem cell (blue), with individual chromosomes occupying distinct spatial territories (colored differently). Here, 982 transcription active sites, corresponding to individual genes, are present in this cell.

Credit

Cai laboratory / Cell

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