Untreated Lesion (IMAGE) University of Pennsylvania School of Medicine Caption Using resiquimod on some CTCL lesions has a systemic effect, which can be seen in significantly diminished lesions that did not directly receive treatment. Credit Penn Medicine Usage Restrictions Credit: Penn Medicine License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.