Immune-Based Therapy in Mice Shows Promise against Pancreatic Cancer (IMAGE)
Caption
Pancreatic tumors are surrounded by a protective "nest" made of fibrotic scar tissue and the cells that manufacture it (red). A new study in mice demonstrates that disrupting this fibrous tissue makes immune therapy and chemotherapy more effective in attacking tumors of the pancreas. Based on the study's findings, doctors at Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital are conducting a phase 1 clinical trial in patients with advanced pancreatic cancer that will test the safety of this drug combination when given along with standard chemotherapy.
Credit
DeNardo Lab
Usage Restrictions
None
License
Licensed content