A Test to Spot Cancer Cells' Achilles' Heels (IMAGE)

Cold Spring Harbor Laboratory

A Test to Spot Cancer Cells' Achilles' Heels

Caption

In leukemia cells, the CRISPR-based method surveyed about 200 potential drug targets in proteins and successfully identified the 6 already known (red spikes) -- most of which are at the focus of existing drug development efforts-- and found an additional 19 targets (grey spikes) never before recognized. The spikes indicate the degree to which blocking specific receptors will cause cancer cells to die.

Credit

Vakoc Lab, CSHL

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