Heart Arteries IRS-1 (IMAGE)

University of North Carolina Health Care

Heart Arteries IRS-1

Caption

Top Row: Heart arteries in normal mice, diabetic mice, and normal mice with deleted IRS-1 gene. Bottom row: when artery is wounded, diabetic mice with less IRS-1 and normal mice with deleted IRS-1 gene show much greater blockage due to over-proliferation of smooth muscle cells.

Credit

Clemmons Lab, UNC School of Medicine

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