Muscle Cells, UC San Diego School of Medicine, Yeo Lab (IMAGE)

University of California - San Diego

Muscle Cells, UC San Diego School of Medicine, Yeo Lab

Caption

These are muscle cells from a patient with myotonic dystrophy type I, untreated (left) and treated with the RNA-targeting Cas9 system (right). The MBNL1 protein is in green, repetitive RNA in red and the cell's nucleus in blue. MBNL1 is an important RNA-binding protein and its normal function is disrupted when it binds repetitive RNA. In the treated cells on the right, MBNL1 is released from the repetitive RNA.

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UC San Diego Health

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