Structure of Ribosomal Protein and Its Chaperone (IMAGE)

California Institute of Technology

Structure of Ribosomal Protein and Its Chaperone

Caption

Structural rendering of a ribosomal protein (yellow and red) bound to its chaperone (blue). By capturing an atomic-resolution snapshot of the pair of proteins interacting with each other, Ferdinand Huber, a graduate student in the lab of André Hoelz revealed that chaperones can protect their ribosomal proteins by tightly packaging them up. The red region illustrates where the dramatic shape alterations occur when the ribosomal protein is released from the chaperone during ribosome assembly.

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Huber and Hoelz/Caltech

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