Handel, CCR2 and inhibitors, Skaggs School of Pharmacy and Pharmaceutical Sciences UC San Diego (IMAGE)

University of California - San Diego

Handel, CCR2 and inhibitors, Skaggs School of Pharmacy and Pharmaceutical Sciences UC San Diego

Caption

Right: Structure of CC chemokine receptor 2 (CCR2) bound to two inhibitors (pink and yellow). Left: Normally, chemokines outside the cell bind CCR2 and the receptor transmits that signal inside the cell via G proteins. Inhibitors block this signal transmission.

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Irina Kufareva, PhD, UC San Diego

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