HLA-B*52:01-C*12:02 aplotype: Protective for AIDS Progression and Susceptive to Autoimmune Diseases (IMAGE)

Kumamoto University

HLA-B*52:01-C*12:02 aplotype: Protective for AIDS Progression and Susceptive to Autoimmune Diseases

Caption

The HLA-B*52:01 and -C*12:02-restricted CTLs strongly suppress HIV-1 replication resulting in slower disease progression. In contrast, the HLA-B*52:01-C*12:02 haplotypes are susceptible to autoimmune diseases.

Credit

Professor Masafumi Takiguchi

Usage Restrictions

This image may only be used in conjunction with the accompanying release, or stories written about the work described in the release with reference to the original work.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.