Solid-State Nanopore with DNA Origami 'Gatekeeper' (IMAGE)

Technical University of Munich (TUM)

Solid-State Nanopore with DNA Origami 'Gatekeeper'

Caption

This illustration shows how a DNA origami nanoplate with a central aperture can serve as a smart lid or "gatekeeper" for a solid-state nanopore sensor. Researchers at the Technische Universitaet Muenchen have demonstrated that this arrangement can be used to filter biomolecules by size or to "fish" for specific target molecules by placing single-strand DNA receptors inside the aperture as "bait." With further research, they suggest, it might be possible to use such single-molecule sensors as the basis of a novel DNA sequencing system.

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TU Muenchen

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