Immature <i>Rous sarcoma</i> Virus (IMAGE)
Caption
A team of computational and experimental researchers at the University of Illinois have provided an atomic structure of the immature retroviral lattice for the Rous sarcoma virus. The multi-domain RSV model was derived through a combination of state-of-the-art modeling techniques, including, cryo-EM-guided homology modeling, large-scale molecular dynamics simulations using enhanced sampling capabilities available in NAMD, together with experimental measurements such as X-ray crystallography and a wealth of biochemical data.
Credit
Boon Chong Goh, Theoretical and Computational Biophysics Group, Beckman Institute for Advanced Science and Technology, University of Illinois
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