CF Islet Cells (IMAGE)
Caption
A new University of Iowa study suggests there are two root causes of a type of diabetes associated with cystic fibrosis (CF). Using a ferret model of CF, the study shows that CF progressively damages the pancreas, disrupting insulin production. More surprisingly, the study also found that CF disrupts the pancreas' insulin-producing islet cells from birth, well before the physical damage occurs. The image shows a confocal 3D rendering of an isolated CF ferret islet stained for insulin (red), glucagon (green), and DAPI nuclear stain (blue), superimposed over a background ferret pancreas section similarly stained for the same antigens.
Credit
University of Iowa
Usage Restrictions
May be used for informational and educational purposes only. Please credit the University of Iowa.
License
Licensed content