NIX Protein in Common Precursor Lesions (IMAGE)

Cold Spring Harbor Laboratory

NIX Protein in Common Precursor Lesions

Caption

Evidence of activity involving the NIX protein (brown staining) is seen in common precursor lesions (PanIN) for pancreatic cancer. NIX activity escalates in full pancreatic ductal adenocarcinoma (PDAC), the most common of pancreas cancers. NIX is directly responsible for triggering mitophagy, or "self eating" of mitochondria.

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Tuveson lab/CSHL

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