Study of Circular DNA Comes Full Circle with Use of Old Technique (IMAGE)

University of Texas at Dallas

Study of Circular DNA Comes Full Circle with Use of Old Technique

Caption

To purify a sample of DNA and extract the circular DNA, University of Texas at Dallas researchers used a 50-year-old lab technique. They added DNA to a dense salt solution containing cesium chloride in a small test tube, then spun the sample in an ultracentrifuge at very high speeds. Circular DNA is denser and concentrates in a band near the bottom of the tube.

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University of Texas at Dallas

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