Lewy Body Pathology (IMAGE) Oregon Health & Science University Caption This image shows abnormal aggregated alpha-synuclein Lewy pathology within neurons of brain's hippocampus in a mouse model of Parkinson's disease and dementia with Lewy bodies. New research suggests that alpha-nuclein proteins repair DNA breaks within the nucleus of brain cells. When they cluster outside the nucleus, as shown here, it can lead to cellular dysfunction and death. Credit Oregon Health & Science University Usage Restrictions Oregon Health & Science University offers select multimedia assets for use by news outlets. (Commercial use is prohibited without prior written consent.) When using these materials, please: Credit photos and video with "Oregon Health & Science University." Do not alter the content/nature of the photo. Color correction and cropping are allowed. For more information, please contact OHSU Strategic Communications at firstname.lastname@example.org or 503-494-8231. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.