Helical vs. Random Coil Polymers as Gene Delivery Agents (IMAGE)

University of Illinois at Urbana-Champaign, News Bureau

Helical vs. Random Coil Polymers as Gene Delivery Agents

Caption

Polymers as gene delivery agents. Helical charged polypeptides, left, deliver DNA to the cell by rupturing the endosomal membrane. Random-coil polymers, right, do not rupture the membrane, so the DNA is not released inside the cell.

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Nathan Gabrielson

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