Cryo Electron Microscopy Shows How Ribosome Scans mRNA (VIDEO)
Caption
Structure of the human translation initiation complex. Although nearly all our cells contain our entire genome, cells use different subsets of genes to make the proteins they need to perform their various functions. This requires precise control over the processes by which the DNA is first transcribed to produce mRNA and then mRNA is translated during protein synthesis. Researchers at UC Davis and the MRC Laboratory of Molecular Biology have now solved the structure of the protein complex formed when mRNA is being scanned to find the start codon, providing new understanding of the molecular mechanisms underpinning initiation of translation.
Credit
Ramakrishnan Lab, Laboratory of Molecular Biology, U.K.
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