Rapid SUMOylation of Cell Surface Cardiac Sodium Channels Causes Late Sodium Current in Response (IMAGE)

University of California - Irvine

Rapid SUMOylation of Cell Surface Cardiac Sodium Channels Causes Late Sodium Current in Response

Caption

New research shows how rapid SUMOylation of cell surface cardiac sodium channels causes late sodium current in response to hypoxia, a challenge that confronts many people with heart disease. This discovery offers new targets for therapeutics to prevent late current and arrhythmia associated with heart attacks, chronic heart failure and other life-threatening low oxygen cardiac conditions.

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UCI School of Medicine

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