Diseases of Despair (AUDIO) Penn State Your browser does not support the audio element. Caption For the first time in nearly 100 years, life expectancy is decreasing in the United States. In this episode, Dr. Larry Sinoway discusses the decline and how it relates to the diseases of despair. He also discusses Penn State's efforts in the Commonwealth to address these diseases. Engage is a podcast of Penn State Clinical and Translational Science Institute. In each episode, you will learn about the research process and how Penn State is helping to improve the health of our neighbors and communities. Credit Penn State Clinical and Translational Science Institute Usage Restrictions non commercial use only License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.