Hypothetical model of the function of EED in hippocampal development (IMAGE)

Chinese Academy of Sciences Headquarters

Hypothetical model of the function of EED in hippocampal development

Caption

(Left) In normal dentate gyrus, EED binds to EZH2, SUZ12 and RbAP46/48 to form an interactive PRC2 complex which regulates neurogenesis in the dentate gyrus. (Right) inactivation of EED leads to a remarkable malformation of the dentate gyrus.

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Liu Changmei

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