An Up-Close View Of Myoblast Fusion (IMAGE)

Tata Institute of Fundamental Research

An Up-Close View Of Myoblast Fusion

Caption

A tomogram-derived scheme shows the interface between a Drosophila flight muscle myotube and a closely apposed myoblast as they fuse with one another. Dhanyasi et al. suggest that contact sites (green) within the apposed surface membranes (pink) give rise to small pores (red), which then expand, leading to cytoplasmic continuity and complete fusion.

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Image copyright 2015 Dhanyasi et al., Journal of Cell Biology

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Image copyright 2015 Dhanyasi et al., Journal of Cell Biology

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