Spine Density Reduced in Mutant SETD1A Mice (IMAGE)

NIH/National Institute of Mental Health

Spine Density Reduced in Mutant SETD1A Mice

Caption

Mutant mice with impaired function of the SETD1A gene showed abnormalities in the neuronal machinery by which brain cells communicate. For example, there were fewer-than-normal spines (right), needed to relay signals, on branches of neurons -- compared to those in wild type mice (left).

Credit

Jun Mukai/Gogos Lab/Columbia's Zuckerman Institute

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