GAPLINC graphic (IMAGE)

University of California - Santa Cruz

GAPLINC graphic

Caption

GAPLINC, a highly conserved long noncoding RNA, modulates the immune response during endotoxic shock. Reducing or eliminating GAPLINC led to enhanced expression of inflammatory genes in both mouse and human cells. In a mouse model of sepsis, knockout mice without GAPLINC were protected from endotoxic shock.

Credit

Apple Vollmers

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