Disabling Cell Defenses (IMAGE)

American Society for Biochemistry and Molecular Biology

Disabling Cell Defenses

Caption

During infection, Salmonella delivers a family of zinc metalloprotease effector proteins (green) into host cells, sabotaging the host immune response. These effectors interact with and then cut a subset of host NF-kB transcription factors (yellow), which are proteins that normally function to turn on immune-related genes following the detection of the pathogen.

Credit

Teresa Thurston

Usage Restrictions

Use only with attribution

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.