pAgo (IMAGE) Hong Kong University of Science and Technology Caption R545 is critical in DNA cleavage of TtAgo, while R486 plays a negligible role. (Left) Catalytic tetrad with plugged-in glutamate finger (yellow). (Right) Credit Hong Kong University of Science and Technology Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.