Retrotransposons (IMAGE) UT Southwestern Medical Center Caption This illustration depicts how retrotransposons are "handcuffed" by the tumor suppressor gene p53. But when p53 is lost, these mobile elements can erupt. Credit Study authors Amanda Jones and Bhavana Tiwari. Artwork by Angela Diehl. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.