Rat Amygdala Pre- and Post-Antibiotics (IMAGE)
Caption
There are more neurons in the central amygdala of a rat with an intact gut microbiome (no antibiotic treatment) undergoing withdrawal from oxycodone (left) and fewer neurons in the central amygdala of a rat with a depleted gut microbiome depleted (due to antibiotic treatment) in withdrawal (right). A decrease in neurons recruited in the central amygdala could result in fewer withdrawal symptoms, leading to higher risk of drug abuse.
Credit
UC San Diego Health Sciences
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