Direct Reprogramming (IMAGE) University of Pennsylvania School of Medicine Caption Dermal fibroblasts are directly reprogrammed to pigmented melanocytes by three transcription factors (SOX10, MITF and PAX3). Credit Ruifeng Yang, Perelman School of Medicine, University of Pennsylvania Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.