A New Algorithm Called DeMAND Identifies the Genes Involved in Implementing a Drug's Effects. (VIDEO)

Columbia University Irving Medical Center

Caption

By analyzing drug-induced changes in disease-specific patterns of gene expression, a new algorithm called DeMAND identifies the genes involved in implementing a drug's effects. The method could help predict undesirable off-target interactions, suggest ways of regulating a drug's activity, and identify novel therapeutic uses for FDA-approved drugs, three critical challenges in drug development. GIF version here: http://newsroom.cumc.columbia.edu/?p=34484

Credit

Califano lab/Columbia University Medical Center

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.