Copper Binding to Enzyme (IMAGE)

University of California - Berkeley

Copper Binding to Enzyme

Caption

The crystal structure of the cAMP-degrading enzyme phosphodiesterase PDE3B, showing two magnesium atoms (green) in the active site. Copper binds one of the amino acid residues in the pink loop at the left, blocking the activity of the enzyme.

Credit

Lakshmipriya Krishnamoorthy and Joseph Cotruvo Jr., UC Berkeley

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