Growing Optimism in Huntington's Disease Research (VIDEO)
Caption
Jonathan Fox, professor of veterinary science and the Neuroscience Program at the University of Wyoming, has a research program that uses cell and mouse models of the human neurodegenerative disease, Huntington's disease. Huntington's disease, which affects about 30,000 people in the United States, is caused by a protein called huntingtin that, when in the mutant form, misfolds and accumulates in neurons. This eventually results in degeneration in brain areas important for movement, mental health and memory. Currently there are no treatments that are effective in slowing progression of the human disease, but Fox and his research team seek to understand disease mechanisms and develop effective therapeutic approaches in mice.
Credit
Ali Grossman, University of Wyoming
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