Antibiotic compound bound to gonorrhea bacteria ribosome (IMAGE)

Penn State

Antibiotic compound bound to gonorrhea bacteria ribosome

Caption

A new antibiotic compound clears infection of multi-drug resistant gonorrhea in mice in a single oral dose, according to a new study. The compound, MBX-4132, binds to the bacterial ribosome and, in so doing, displaces a region of a protein (bL27, purple) that is critical to the trans-translation pathway in bacteria.

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Dunham Lab, Emory University

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