SMARCAD1 Pinball (IMAGE) University of California - San Diego Caption This is an artistic rendering showing that the interaction between SMARCAD1 and H3R26Cit modified histones can be skillfully manipulated -- as if in a game of pinball -- to regulate the switch of embryonic stem cells from the naïve to the primed pluripotent state. Credit Victor Leshyk Usage Restrictions Please credit: Victor Leshyk License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.