Structural Modeling of RNA (IMAGE) University of North Carolina Health Care Caption The left panel illustrates the structure of a metal-binding RNA. Each nucleotide is colored according to its experimentally determined exposure to the outside solvent. Blue nucleotides tend to be buried inside the structure, and red nucleotides are mostly exposed to the solvent on the surface of the molecule. Using the solvent exposure information derived from experiments, scientists can perform calculations to determine a set of possible structural models (right panel). A benchmark of the method demonstrates excellent agreement with known structures. Credit University of North Carolina at Chapel Hill Usage Restrictions Credit the University of North Carolina at Chapel Hill License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.