Structural Modeling of RNA (IMAGE)
Caption
The left panel illustrates the structure of a metal-binding RNA. Each nucleotide is colored according to its experimentally determined exposure to the outside solvent. Blue nucleotides tend to be buried inside the structure, and red nucleotides are mostly exposed to the solvent on the surface of the molecule. Using the solvent exposure information derived from experiments, scientists can perform calculations to determine a set of possible structural models (right panel). A benchmark of the method demonstrates excellent agreement with known structures.
Credit
University of North Carolina at Chapel Hill
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Credit the University of North Carolina at Chapel Hill
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